Partitioning of arsenic in organisms and the role of arsenic in cellular metabolism

Partitioning of arsenic in organisms and the role of arsenic in cellular metabolism

Project Information

Team

Teresa Gonzalez de Chavez Capilla, Simon Foster, Bill Maher, Tasmin Kelly and George Raber (University of Graz)



Project Summary

Animals are exsposed to arsenic in their food and water. The concentrations of arsenic aminals are exposed to will influence their potential for adverse health effects. This research will explain why some arsenic species enter the cell more readily than others. The researchers will determine if arsenic can form lipid complexes in cells and if these lipid arsenic complexes are further metabolised into more toxic compounds. The researchers will also determine how arsenic is excreted from cells as this aspect is poorly understood. This is the first research to assess the potential for the non-mediated transport of arsenic in cells.