PhD opportunity – Virulence factors in rabbit calicivirus infections
Posted 6th November 2017
This project would suit a student with interest and a strong background in molecular virology, cell culture and/or immunology
The rabbit haemorrhagic disease virus (RHDV) is a highly virulent calicivirus that kills over 90% of susceptible rabbits within 72 hrs post infection.
We recently found that the RNA-dependent RNA polymerase of RHDV has some unexpected characteristics, such as the unusually high temperature optimum of 40–45°C and the ability to redistribute Golgi membranes.
The successful candidate will continue to investigate the functions of the non-structural proteins of RHDV with a focus on potential interactions with the innate and adaptive immune systems.
The successful candidate will be based at CSIRO’s Black Mountain Laboratories (Canberra) and the University of Canberra.
The successful candidate will receive a 3-year scholarship (ca. $26,500 per year, tax-free) with the possibility of further top-ups.
Urakova et al. 2015, Virology 484:69; Urakova et al. 2016, Viruses 8(4): E100; Urakova et al. 2017, Viruses 9(8):202; and Hall et al. 2017, PLoS One 12(3):e0173727.
Dr Michael Frese (email@example.com); Dr Tanja Strive (firstname.lastname@example.org); Dr Robyn Hall (email@example.com)